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CATPB

品牌
Sigma-Aldrich
CAS
1322598-09-3
货号
SML1782
包装型号
规格纯度
≥98% (HPLC)
参考价格
1548.78 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
1322598-09-3
CATPB
(S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

CATPB is an acetamidophenylbutanoate derivative with inverse agonist and antagonist activity against human, but not mouse or rat, FFA2 (GPR43). CATPB inhibits both constitutive and propionate (C3) -stimulated hFFA2 GTPγS incorporation (IC50 ~35 and 320 nM, respectively; [C3] = EC80, ~125 nM), as well as C3-induced hFFA2 G159E activity (IC50 ~400 nM). CATPB is shown to inhibit C3-induced intracellular ERK phosphorylation in hFFA2-expressing cells (IC50 ~3 μM against 10 mM C3).

基本信息

经验(实验)分子式C19H17ClF3NO3
分子量399.79
PubChem化学物质编号329826062
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 10 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(N[C@@H](CC1=CC=C(C(F)(F)F)C=C1)CC(O)=O)CC2=CC=CC(Cl)=C2

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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