FMF-04-159-2

产品名称：

2364489-81-4
FMF-04-159-2
(E)-N-(1-((3-(4-(dimethylamino)but-2-enamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide

产品介绍：

产品说明

生化/生理作用

FMF-04-159-2 is a specific and potent covalent inhibitor Cyclin-dependent kinase 14 (CDK14) in cells that targets CDK14 at C218. FMF-04-159-2 reversibly inhibits CDK2, CDK10, and other TAIRE kinases (CDK15, CDK16, CDK17, and CDK18) with comparable potency to each other. It exhibits mild antiproliferative effects.

基本信息

经验(实验)分子式	C₂₈H₃₀Cl₃N₇O₅S
分子量	683.01
MDL编号	MFCD32182619

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(C1=NNC=C1NC(C2=C(Cl)C=C(Cl)C=C2Cl)=O)NC3CCN(S(=O)(C4=CC=CC(NC(/C=C/CN(C)C)=O)=C4)=O)CC3

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable