Gemifloxacin mesylate

产品名称：

210353-53-0
Gemifloxacin mesylate
7-[(4Z)-3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid monomethanesulfonate
7-(4-Aminomethyl-3-methyloxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1, 4-dihydro-1,8-naphthyridine-3-carboxylic acid mesylate

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

基本信息

经验(实验)分子式	C₁₈H₂₀FN₅O₄ · CH₄O₃S
分子量	485.49
MDL编号	MFCD08277637
PubChem化学物质编号	329825509

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to light brown
溶解性	H₂O: 10 mg/mL, clear
储存温度	room temp
SMILES string	CS(=O)(O)=O.OC(C1=CN(C2CC2)C3=NC(N4C/C(C(CN)C4)=N\OC)=C(F)C=C3C1=O)=O
InChI	1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+;
InChI key	JIYMVSQRGZEYAX-CWUUNJJBSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H341 - H361d - H373
预防措施声明	P202 - P260 - P280 - P308 + P313 - P405 - P501
危险分类	Muta. 2 - Repr. 2 - STOT RE 2
靶器官	Liver
储存分类代码	11 - Combustible Solids
WGK	WGK 3