IMB-10

产品名称：

307525-40-2
IMB-10
3-(2-methylphenyl)-5-(3-phenyl-2-propen-1-ylidene)-2-thioxo-4-thiazolidinone

产品介绍：

产品说明

应用

IMB-10 may be used to study integrin-mediated signaling in tumor cells.

包装

5, 25 mg in glass bottle

生化/生理作用

IMB-10 is a ligand for the αMβ2 integrin that stabilizes the binding of the integrin to endogenous ligands such as proMMP-9 and fibrinogen. IMB-10 blocks migration of lymphocyte cell lines and inhibits leukocyte infiltration in a murine thioglycolate-induced peritonitis.
IMB-10 is a thioxothiazolidine compound that inhibits the infiltration of leukocytes to the site of tumor and blocks the invasion of HSC-3 carcinoma. It modulates the host inflammatory responses and tumor progression.

基本信息

经验(实验)分子式	C₁₉H₁₅NOS₂
分子量	337.46
MDL编号	MFCD20134199
PubChem化学物质编号	329825094
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	yellow
溶解性	DMSO: ≥25 mg/mL
储存温度	2-8℃
SMILES string	Cc1ccccc1N2C(=S)S\C(=C\C=C\c3ccccc3)C2=O
InChI	1S/C19H15NOS2/c1-14-8-5-6-12-16(14)20-18(21)17(23-19(20)22)13-7-11-15-9-3-2-4-10-15/h2-13H,1H3/b11-7+,17-13+
InChI key	UYZLENPCNZVWQZ-QHMSGILQSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3