IMM-01

产品名称：

218795-74-5
IMM-01
N1-(tert-Butyl)-2-(2,4-dihydroxybenzylidene)hydrazine-1-carbothioamide
2-[(2,4-Dihydroxyphenyl)methylene]-N-(1,1-dimethylethyl)-hydrazinecarbothioamide
Intramimic-01

产品介绍：

产品说明

应用

IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs).

包装

5, 25 mg in glass bottle

生化/生理作用

IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer.
IMM-01 binds and activates formin thereby leading to autoinhinition.

基本信息

经验(实验)分子式	C₁₂H₁₇N₃O₂S
分子量	267.35
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to light brown
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable