MRS-1706

产品名称：

264622-53-9
MRS-1706
MRS1706
8-[4-[((4-Acetylphenyl)carbamoylmethyl)oxy]phenyl]-1,3-di(n-propyl)xanthine
N-(4-Acetylphenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide
MRS 1706
N-(4-Acetylphenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide

产品介绍：

产品说明

生化/生理作用

MRS-1706 is a high-affinity, potent and selective adenosine 2B receptor (A2B) antagonist/inverse agonist (human A1/A2A/A2B/A3 Ki = 157/112/1.39/230 nM; rat A1/A2A Ki = 37.6/548 nM). MRS-1706 (20 nM), but not the A2A antagonist SCH 58261 (20 nM), completely blocks the enhancement of electrically evoked tritium overflow from isolated rat tail artery by 10 μM adenosine receptor agonist NECA in the presence of 30 nM A1 antagonist DPCPX.

基本信息

经验(实验)分子式	C₂₇H₂₉N₅O₅
分子量	503.55

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	O=C(COC1=CC=C(C=C1)C2=NC3=C(N2)N(C(N(C3=O)CCC)=O)CCC)NC4=CC=C(C=C4)C(C)=O