您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > PIAA

PIAA

品牌
Sigma-Aldrich
CAS
851814-28-3
货号
SML2564
规格纯度
≥98% (HPLC)
参考价格
1168.11 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
851814-28-3
PIAA
(E)-3-(3-phenylbenzo[c]isoxazol-5-yl)acrylic acid
3-(3-phenyl-2,1-benzisoxazol-5-yl)-2-propenoic acid
产品介绍:

产品说明

生化/生理作用

PIAA is an inhibitor of TANK binding kinase 1 (TBK1) and IKB kinase epsilon (IKKε) that has been shown to promote regeneration of pancreatic β-cells. PIAA improved function and replication of mammalian β-cells including primary human β-cells and induced β-cell proliferation in streptozotocin-induced diabetic mice resulting in increased pancreas insulin content and improved glycemic control. PIAA exhibited an IC50 value of 400 nM for TBK1 and 1.07 μM for IKKε with minimum toxicity

基本信息

经验(实验)分子式C16H11NO3
分子量265.26

产品性质

测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear (warmed)
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品