产品说明
应用
SR 57227A may be used in 5-HT3-mediated cell signaling studies.
包装
5 mg in glass bottle
生化/生理作用
SR 57227A is a highly selective of central and peripheral 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreased isolation-induced aggressive behavior.
Potent and selective 5-HT3 serotonin receptor agonist.
基本信息
| 经验(实验)分子式 | C10H14ClN3 · HCl |
| 分子量 | 248.15 |
| MDL编号 | MFCD01756430 |
| PubChem化学物质编号 | 24278109 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 形式 | solid |
| 颜色 | white |
| 溶解性 | H2O: soluble 9 mg/mL |
| SMILES string | Cl.NC1CCN(CC1)c2cccc(Cl)n2 |
| InChI | 1S/C10H14ClN3.ClH/c11-9-2-1-3-10(13-9)14-6-4-8(12)5-7-14;/h1-3,8H,4-7,12H2;1H |
| InChI key | FUMINTAAUJUVMP-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242) |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H315 - H319 - H335 |
| 预防措施声明 | P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
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