SW02

产品名称：

1010820-68-4
SW02
4-(4-Bromophenyl)-5-(ethoxycarbonyl)-3,4-dihydro-6-methyl-2-oxo-1(2H)-pyrimidinebutanoic acid methyl ester

产品介绍：

产品说明

应用

SW02 may be used in Hsp70-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

SW02 is a specific activator/agonist of Hsp70. Hsp70 is of particular interest in diseases caused by protein misfolding, such as tau and Aβ in Alzheimer′s. SW02 increases Hsp70 ATPase activity, resulting in increased tau protein but not other disease-related proteins in cells. Hsp70 prevents aggregation of Aβ peptide, as shown by treatment with SW02.

基本信息

经验(实验)分子式	C₁₉H₂₃BrN₂O₅
分子量	439.30
MDL编号	MFCD17215960
PubChem化学物质编号	329824558
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to off-white
溶解性	DMSO: ≥20 mg/mL
储存温度	2-8℃
SMILES string	CCOC(=O)C1=C(C)N(CCCC(=O)OC)C(=O)NC1c2ccc(Br)cc2
InChI	1S/C19H23BrN2O5/c1-4-27-18(24)16-12(2)22(11-5-6-15(23)26-3)19(25)21-17(16)13-7-9-14(20)10-8-13/h7-10,17H,4-6,11H2,1-3H3,(H,21,25)
InChI key	YFZRMRYVWWUQME-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301
预防措施声明	P301 + P310
危险分类	Acute Tox. 3 Oral
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable