1,1′-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2<I>H</I>-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis1-dodecanone

产品名称：

144337-18-8
YM-26734
1,1′-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis1-dodecanone

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. The IC₅₀against rabbit platelet derived sPLA2 is 85 nM. YM-26734 is active against, but less potent for group I (pancreatic) sPLA2 (porcine pancreatic enzyme IC₅₀ = 7 μM), and does not inhibit intracellular PLA2 isoforms.
YM-26734 is a natural product analog and a derivative of YM-26567-1, which is found in the fruit of Horsfieldia amygdaline. It exhibits a broad inhibitory spectrum towards different sPLA2s.

基本信息

经验(实验)分子式	C₄₅H₆₂O₈
分子量	730.97
MDL编号	MFCD00918068
PubChem化学物质编号	329825731
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	−20℃
SMILES string	OC1=C(C2CC(C3=CC=C(O)C=C3)OC4=C2C=CC(O)=C4)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C(CCCCCCCCCCC)=O
InChI	1S/C45H62O8/c1-3-5-7-9-11-13-15-17-19-21-36(48)41-43(50)40(44(51)42(45(41)52)37(49)22-20-18-16-14-12-10-8-6-4-2)35-30-38(31-23-25-32(46)26-24-31)53-39-29-33(47)27-28-34(35)39/h23-29,35,38,46-47,50-52H,3-22,30H2,1-2H3
InChI key	CEJAYJCUSZHYDS-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable