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ABT-751 hydrochloride

品牌
Sigma-Aldrich
CAS
141450-48-8
货号
SML0131
规格纯度
≥98% (HPLC)
参考价格
1666.25 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
141450-48-8
ABT-751 hydrochloride
N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide hydrochloride
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

ABT-751 is an orally bioavailable vascular disrupting agent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules.
ABT-751, a sulfonamide antimitotic agent, is under clinical trials to treat patients with various malignancies including refractory hematologic malignancies, non-small cell lung cancer (NSCLC), and colon cancer.

特点和优势

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C18H17N3O4S · HCl
分子量407.87
MDL编号MFCD19440802
PubChem化学物质编号329825181
NACRESNA.25

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 pink to purple
溶解性DMSO: ≥15 mg/mL
创始人Abbott
储存温度2-8℃
SMILES stringCl.COc1ccc(cc1)S(=O)(=O)Nc2cccnc2Nc3ccc(O)cc3
InChI1S/C18H17N3O4S.ClH/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13;/h2-12,21-22H,1H3,(H,19,20);1H
InChI keyKWQWWUXRGIIBAS-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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