3-AP

产品名称：

143621-35-6
3-AP
3-Aminopyridine-2-carboxaldehyde thiosemicarbazone
PAN-811

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

3-aminopyridine carboxaldehyde thiosemicarbazone (3-AP) has a IC₅₀ value of 0.3μM. It exhibits anti-proliferative activity in preclinical models of cancer, such as lung cancer. It also has an ability to increase the cytotoxicity, intracellular uptake and DNA incorporation of gemcitabine in vitro.
3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) is a ribonucleotide reductase inhibitor and iron chelator with anti-tumor activity.

基本信息

经验(实验)分子式	C₇H₉N₅S
分子量	195.24
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to light brown
溶解性	DMSO: 10 meq/mL, clear
储存温度	2-8℃
InChI	1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+
InChI key	XMYKNCNAZKMVQN-NYYWCZLTSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H315 - H319 - H335
预防措施声明	P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable