5HPP-33

产品名称：

105624-86-0
5HPP-33
2-[2,6-bis(1-Methylethyl)phenyl]-5-hydroxy-1H-isoindole-1,3(2H)-dione
5-Hydroxy-2-(2,6-diisopropylphenyl)-1H-isoindole-1,3-dione

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM).

基本信息

经验(实验)分子式	C₂₀H₂₁NO₃
分子量	323.39
MDL编号	MFCD03085294
PubChem化学物质编号	329815265
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white to off-white
溶解性	DMSO: >20 mg/mL
储存温度	2-8℃
SMILES string	CC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O
InChI	1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3
InChI key	LAKWINYVWJPHQW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H410
预防措施声明	P273 - P501
危险分类	Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves