产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM).
基本信息
| 经验(实验)分子式 | C20H21NO3 |
| 分子量 | 323.39 |
| MDL编号 | MFCD03085294 |
| PubChem化学物质编号 | 329815265 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | white to off-white |
| 溶解性 | DMSO: >20 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | CC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O |
| InChI | 1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3 |
| InChI key | LAKWINYVWJPHQW-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H410 |
| 预防措施声明 | P273 - P501 |
| 危险分类 | Aquatic Acute 1 - Aquatic Chronic 1 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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