6-硫-2′-脱氧鸟苷

产品名称：

789-61-7
6-Thio-2′-Deoxyguanosine
2′-Deoxythioguanosine
NSC 71261
2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thione (7CI,8CI)
2′-Deoxy-6-thioguanosine
2′-Ddeoxy-6-thio-guanosine
2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-mercaptopurine
6-Thio-dG
6-硫-2′-脱氧鸟苷

产品介绍：

产品说明

应用

6-Thio-2′-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.

包装

5, 25 mg in glass bottle

生化/生理作用

6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.

基本信息

经验(实验)分子式	C₁₀H₁₃N₅O₃S
分子量	283.31
PubChem化学物质编号	329825770
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to brown
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	−20℃
SMILES string	S=C1C2=C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)N=C(N)N1
InChI	1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5-,6-/m1/s1
InChI key	SCVJRXQHFJXZFZ-HSUXUTPPSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable