Thymosin в4 (1-4) trifluoroacetate

产品名称：

1796568-94-9
Ac-SDKP trifluoroacetate
Ac-Ser-Asp-Lys-Pro-OH trifluoroacetate
Thymosin в4 (1-4) trifluoroacetate
Ac-SDKP-OH trifluoroacetate
Tв4 (1-4) trifluoroacetate
Goralatide trifluoroacetate
N-acetyl-L-seryl-L-a-aspartyl-L-lysyl-L-proline trifluoroacetate
AcSDKP trifluoroacetate
N-acetyl-Ser-Asp-Lys-Pro-OH trifluoroacetate

产品介绍：

产品说明

生化/生理作用

Originally characterized as a "spleen colony-forming units (CFU-S) inhibitor" for its activity against hematopoietic pluripotent stem cell proliferation, Ac-SDKP (Goralatide) is an immunomodulatory and pro-angiogenic tetrapeptide derived from the N-terminal end of thymosin β4 (Tβ4 aa 1-4) via sequential enzymatic actions of meprin-α and prolyl-oligopeptidase (POP), while angiotensin converting enzyme (ACE) mediates Ac-SDKP degradation. In animal heart, kidney and brain injury studies, Ac-SDKP ameliorates end-organ damage by promoting angiogenesis, as well as by reducing inflammation and fibrosis.

基本信息

经验(实验)分子式	C₂₀H₃₃N₅O₉ · xC₂HF₃O₂
分子量	487.50 (free base basis)

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	lyophilized powder
颜色	white to off-white
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable