产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
AEG3284 is a compound that binds to heat shock protein 90 (HSP90), leading to heat shock factor 1 (HSF1) dependent expression of HSP70, an endogenous inhibitor of c-Jun N-terminal kinase (JNK) activity. Treatment of PC12 cells with AEF3284 blocks JNK dependent apoptosis.
AEG 3482 is an imidazothiadiazole sulfonamide of 281 D with an anti-apoptotic property.
特点和优势
This compound is featured on the MAPKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C10H8N4O2S2 |
| 分子量 | 280.33 |
| MDL编号 | MFCD02064987 |
| PubChem化学物质编号 | 329825272 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | faintly yellow to dark yellow |
| 溶解性 | DMSO: ≥15 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | NS(=O)(=O)c1nn2cc(nc2s1)-c3ccccc3 |
| InChI | 1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16) |
| InChI key | MQUYTXDAVCOCMX-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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