您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > N,N,N-Trimethyl-γ-oxo-1-naphthalenepropanaminium iodide

alpha-NETA

品牌
Sigma-Aldrich
CAS
115066-04-1
货号
SML2731
规格纯度
≥98% (HPLC)
参考价格
911.04 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
115066-04-1
alpha-NETA
2-(alpha-Naphthoyl)ethyltrimethylammonium iodide
N,N,N-Trimethyl-γ-oxo-1-naphthalenepropanaminium iodide
α-NETA
N,N,N-Trimethyl-3-(naphthalen-1-yl)-3-oxopropan-1-aminium iodide
a-NETA
产品介绍:

产品说明

生化/生理作用

Originally identified as a substrate (ChA or choline)-noncompetitive, slowly reversible choline acetyltransferase inhibitor (human ChAT/BuChE/AChE IC50 = 88 nM/33.3 μM/48.6 μM; does not affect mAChRs, AChE, ChE, CrAT, ganglionic or skeletal muscular nAChRs), α-NETA is a fluorescent molecule (Ex 255 & 297 nm; Em 427 nm) also known for its trace amine-associated receptor 5 (TAAR5 EC50 = 150 nM) agonist and chemokine-like receptor-1 antagonist (IC50 = 375 nM; 7 nM chemerin-induced CMKLR1 β-ARR2 recruitment) potencies both in cultures and in animal disease models in vivo (3-20 mg/kg via ip. or sc. in rats & mice).

基本信息

经验(实验)分子式C16H20INO
分子量369.24
MDL编号MFCD00209857

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(C1=CC=CC2=C1C=CC=C2)CC[N+](C)(C)C.[I-]

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品