产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
DDRI-18 (DNA Damage Response Inhibitor-18) inhibits nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, and enhances the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin.
基本信息
| 经验(实验)分子式 | C26H20N6 |
| 分子量 | 416.48 |
| MDL编号 | MFCD01137750 |
| PubChem化学物质编号 | 329825588 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 10 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | NC1=CC=CC(C(N2)=NC(C=C3)=C2C=C3C4=CC5=C(C=C4)N=C(N5)C6=CC(N)=CC=C6)=C1 |
| InChI | 1S/C26H20N6/c27-19-5-1-3-17(11-19)25-29-21-9-7-15(13-23(21)31-25)16-8-10-22-24(14-16)32-26(30-22)18-4-2-6-20(28)12-18/h1-14H,27-28H2,(H,29,31)(H,30,32) |
| InChI key | QROWVLFOWUYBIG-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 - H413 |
| 预防措施声明 | P273 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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