Butanoic acid [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,7,8-trihydroxy-6-indolizinyl ester

产品名称：

121104-96-9
Celgosivir
Butanoic acid (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester
MDL 28,574
6-O-Butyrylcastanospermine
MDL-28574
6-O-Butanoylcastanospermine
Butanoic acid [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,7,8-trihydroxy-6-indolizinyl ester
MDL 28574
BuCast

产品介绍：

产品说明

生化/生理作用

Celgosivir is a prodrug of natural bicyclic iminosugar castanospermine that exhibits antiviral activity in vivo including HCV and dengue. Celgosivir is an inhibitor of α-glucosidases, which inhibits glycoprotein processing in cell culture. Apparently inhibition of α-glucosidases within infected cell prevents secretion of virus.

基本信息

经验(实验)分子式	C₁₂H₂₁NO₅
分子量	259.30
MDL编号	MFCD00886617
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
储存条件	desiccated under inert gas
颜色	white to beige
溶解性	H₂O: 2 mg/mL, clear
储存温度	−20℃
SMILES string	O[C@@H]1[C@@H](OC(CCC)=O)CN2[C@@]([C@@H](O)CC2)([H])[C@H]1O
InChI	1S/C12H21NO5/c1-2-3-9(15)18-8-6-13-5-4-7(14)10(13)12(17)11(8)16/h7-8,10-12,14,16-17H,2-6H2,1H3/t7-,8-,10+,11+,12+/m0/s1
InChI key	HTJGLYIJVSDQAE-VWNXEWBOSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable