产品说明
生化/生理作用
DC260126 is a FFA1 (GPR40) selective antagonist. In FFA1-expressing CHO cells, DC260126 blocks linoleic acid-induced Ca2+ elevation and ERK phosphorylation (IC50 = 6028 μM), as well as palmitic acid potentiated glucose-stimulated insulin secretion. The compound DC260126 blocks MIN6 β cells from palmitic acid-induced ER stress and apoptosis.
基本信息
| 经验(实验)分子式 | C16H18FNO2S |
| 分子量 | 307.38 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | DMSO: 20 mg/mL, clear |
| 储存温度 | −20℃ |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
m.cnreagent.com
