HI-TOPK-032

产品名称：

487020-03-1
HI-TOPK-032
N-(12-Cyanindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide

产品介绍：

产品说明

应用

HI-TOPK-032 has been used as a PDZ binding-kinase (PBK) inhibitor.

包装

5, 25 mg in glass bottle

生化/生理作用

HI-TOPK-032 is a specific TOPK (T-LAK cell–originated protein kinase) inhibitor both in vitro and in vivo. HI-TOPK-032 suppressed tumor growth in a colon cancer xenograft model.
HI-TOPK-032 belongs to the class of ATP-competitive inhibitors. It can also be used as a potent therapeutic for colorectal cancer.

基本信息

经验(实验)分子式	C₂₀H₁₁N₅OS
分子量	369.40
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	orange to dark red
溶解性	DMSO: 3 mg/mL, clear (warmed)
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable