FQI1

产品名称：

599151-35-6
FQI1
8-(2-Ethoxyphenyl)-7,8-dihydro-1,3-Dioxolo[4,5-g]quinolin-6(5H)-one

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

FQI1 inhibits the DNA-binding activity of LSF, a ubiquitous transcription factor that is up regulated in many hepatocellular carcinomas (HCC). FQI1 inhibits LSF-dependent luciferase reporter expression, blocks proliferation in cancer cell lines, and induces apoptosis in liver cancer cells but is not toxic to primary hepatocytes. FQI1 also inhibits tumor growth in a mouse HCC xenograft model.

基本信息

经验(实验)分子式	C₁₈H₁₇NO₄
分子量	311.33
MDL编号	MFCD03632583
PubChem化学物质编号	329825408
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL (clear solution)
储存温度	2-8℃
SMILES string	O=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
InChI	1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
InChI key	YKSYGLXHLSPWLB-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3