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MCB-613

品牌
Sigma-Aldrich
CAS
296792-62-6
货号
SML1567
规格纯度
≥98% (HPLC)
参考价格
1117.23 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
296792-62-6
MCB-613
4-Ethyl-2,6-bis(pyridin-3-ylmethylene)cyclohexanone
产品介绍:

产品说明

一般描述

MCB-613 (4-Ethyl-2,6-bis-pyridin-3-ylmethylene-cyclohexanone) belongs to the chalcone class of compounds. It is an anti-neoplastic compound.

应用

MCB-613 has been used to study the molecular mechanism of MCB-613-induced cell death.

包装

5, 25 mg in glass bottle

生化/生理作用

MCB-613 is capable of inducing the transcriptional activity of steroid receptor coactivators (SRCs).
MCB-613 is a pan-Steroid Receptor Coactivator (SRC) stimulator. There are three steroid receptor coactivators (SRC) that interact with transcription factors and whose overexpression is assciated with a number of cancers, particularly breast cancer. MCB-613 overstimulates SRC activity in cancer cells resulting in excessive generation of reactive oxygen species (ROS), leading to cell stress and death by a process called paraptosis. MCB-613 is a cytotoxic molecule which can kill various human cancer cell lines, like HepG2 (liver), PC-3 (prostate) and MCF-7 (breast) cells.

基本信息

经验(实验)分子式C20H20N2O
分子量304.39
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 5 mg/mL, clear (warmed)
储存温度2-8℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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