(2S-<I>trans</I>)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate

(2S-trans)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate

品牌

Sigma-Aldrich

CAS

111466-41-2

货号

M7065

包装型号

25 MG, ≥98% (HPLC)

规格纯度

≥98% (HPLC)

参考价格

13714.1 元 *本价格含增值税费

促销

数量

产品名称：

111466-41-2
MK-912 hydrochloride hydrate
L-657,743
(2S-trans)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate

产品介绍：

产品说明

应用

MK-912 hydrochloride hydrate has been used:

as an α₂-adrenoceptor antagonist in biophysical studies
to study its selectivity towards the C-terminal half of α_2C-adrenoceptor
an α_2C-adrenoceptor antagonist in autoradiography studies

包装

5, 25 mg in glass bottle

生化/生理作用

Selective α₂-adrenoceptor antagonist

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Material is hygroscopic.

基本信息

经验(实验)分子式	C₂₀H₂₅N₃O₂ · xHCl · yH₂O
分子量	339.43 (anhydrous free base basis)
PubChem化学物质编号	24278567
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: soluble 16 mg/mL
创始人	Merck & Co., Inc., Kenilworth, NJ, U.S.
SMILES string	O.Cl.CN1CCC2(CCN3CCc4c(oc5ccccc45)C3C2)N(C)C1=O
InChI	1S/C20H25N3O2.ClH.H2O/c1-21-11-8-20(22(2)19(21)24)9-12-23-10-7-15-14-5-3-4-6-17(14)25-18(15)16(23)13-20;;/h3-6,16H,7-13H2,1-2H3;1H;1H2
InChI key	WVVGVFGUHPXSJZ-UHFFFAOYSA-N
Gene Information	human ... ADRB2(154)

MK-912 hydrochloride hydrate

(2S-trans)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate