NCT-503 Inactive Control

产品名称：

1914971-16-6
NCT-503 Inactive Control
N-(4,6-Dimethylpyridin-2-yl)-4-(pyridin-4-yl)piperazine-1-carbothioamide

产品介绍：

产品说明

应用

NCT-503 Inactive Control has been used as a small molecule inhibitor of phosphoglycerate dehydrogenase in neuroblastoma cells.

包装

5, 25 mg in glass bottle

生化/生理作用

NCT-503 Inactive Control is the inactive control probe for NCT-503, which is an inhibitor of phosphoglycerate dehydrogenase (PHGDH), the enzyme that catalyzes the first, rate-limiting step of glucose-derived serine synthesis. NCT-503 Inactive Control has an IC₅₀ value >57 μM for PHGDH. NCT-503 has an IC₅₀ value of 2.5 μM for PHGDH. NCT-503 Inactive Control is water soluble and has good stability, similar to NCT-503.

推荐产品

The active PHGDH inhibitor, NCT-503, is available from Sigma. To learn more about and purchase NCT-503, click here.

基本信息

经验(实验)分子式	C₁₇H₂₁N₅S
分子量	327.45
PubChem化学物质编号	329826006
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	CC1=CC(NC(N2CCN(C3=CC=NC=C3)CC2)=S)=NC(C)=C1
InChI	1S/C17H21N5S/c1-13-11-14(2)19-16(12-13)20-17(23)22-9-7-21(8-10-22)15-3-5-18-6-4-15/h3-6,11-12H,7-10H2,1-2H3,(H,19,20,23)
InChI key	ITLPIAAGIQAGRA-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315
危险分类	Skin Irrit. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable