产品说明
生化/生理作用
PS432 is an allosteric inhibitor of Protein Kinase C (PKC) that targets regulatory site (PIF-pocket) present in the kinase domain. PS432 potently inhibits non-small cell lung cancer cells proliferation and tumor growth without side effects in a mouse xenograft model.
基本信息
经验(实验)分子式 | C25H19ClN2O5S |
分子量 | 494.95 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
运输 | ambient |
储存温度 | 2-8℃ |
SMILES string | O=C1C(O)=C(C(OCC)=O)C(C2=CC=C(C3=CC=C(Cl)C=C3)O2)N1C4=NC(C=CC(C)=C5)=C5S4 |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich