5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3′,2′:3,4]diazepino[6,7,1-hi]indole hydrochloride

产品名称：

PSEM308 hydrochloride
5-Methyl-5,8,9,10,11a,12-hexahydro-4H-8,11-ethanopyrido[3′,2′:3,4]diazepino[6,7,1-hi]indole hydrochloride
5-Methyl-3,4,14-triazapentacyclo[12.2.2.14,7.02,13.011,19]nonadeca-2,7(19),8,10-tetraene hydrochloride
PSEM 308 hydrochloride
Pharmacologically selective effector molecule 308, hydrochloride

产品介绍：

产品说明

生化/生理作用

SEM308 is a pharmacologically selective effector molecule (PSEM) that acts as a selective agonist in vitro and in vivo for chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F or L141F/Y115F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC), including glycine receptor (PSAM^L141F-GlyR & PSAM^{L141F/Y115F-GlyR}) and 5-HT3 (PSAM^{L141F/Y115F-5-HT3}).

基本信息

经验(实验)分子式	C₁₇H₂₁N₃ · HCl
分子量	303.83
MDL编号	MFCD31689250

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	CC1CC2=CC=CC3=C2N1N=C(C4CCN5CC4)C5C3.Cl

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable