Rinvanil

产品名称：

457643-60-6
Rinvanil
(9Z,12R)-12-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-9-octadecenamide
N-Vanillylricinoleamide

产品介绍：

产品说明

生化/生理作用

Rinvanil is a Capsaicin analogue that potently activates transient receptor potential vanilloid 1 (TRPV1) channels. Rinvanil induces neuroprotective mild hypothermia in ischemic brain injured mice through TRPV1 activation. Rinvanil exhibits potent anticancer activity in cancer cell lines including cervical (HeLa, CaSKi, ViBo) and leukemia (P388, J774, WEHI-3) cell lines. Rinvanil is not cytotoxic to normal lymphocytes.
TRPV1 (transient receptor potential vanilloid 1) is a capsaicin receptor. It is strongly expressed in sensory neurons and participates in pain perception. In brain, it regulates neuronal function, motor behaviour and neuroinflammation. Capsaicin plays an important role in the activation of TRPV1.

基本信息

经验(实验)分子式	C₂₆H₄₃NO₄
分子量	433.62
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	oil
颜色	colorless to yellow
储存温度	2-8℃

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable