雷夫康唑

产品名称：

182760-06-1
Ravuconazole
4-[2-[(1R,2R)-2-(2,4-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile
BMS-207147
ER-30346
雷夫康唑

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Ravuconazole (BMS-207147) is a potent and broad spectrum triazole antifungal. Ravuconazole is an inhibitor of sterol biosynthesis by inhibition of cytochrome P450 14α-demethylase, an enzyme in the sterol biosynthesis pathway that leads from lanosterol to ergosterol.

基本信息

经验(实验)分子式	C₂₂H₁₇F₂N₅OS
分子量	437.47
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (NMR)
形式	powder
旋光性	[α]/D -27 to -33°, c = 1 in methanol
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	−20℃
InChI	1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30,11-29-13-26-12-27-29)18-7-6-17(23)8-19(18)24/h2-8,10,12-14,30H,11H2,1H3/t14-,22+/m0/s1
InChI key	OPAHEYNNJWPQPX-RCDICMHDSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P280 - P305 + P351 + P338 - P337 + P313
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable