Sitamaquine tosylate

产品名称：

1019640-33-5
Sitamaquine tosylate
N-[6-(Diethylamino)hexyl]-6-methoxy-4-methylquinolin-8-amine tosylate
6-Methoxy-8-(6-diethylaminohexylamine)-4-methylquinoline tosylate
WR-6026
N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine tosylate
NSC 2452

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.
Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.

基本信息

经验(实验)分子式	C₂₁H₃₃N₃O · C₇H₈O₃S
分子量	515.71
MDL编号	MFCD17392572
PubChem化学物质编号	329825952

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 15 mg/mL, clear
储存温度	2-8℃
SMILES string	CC1=C(C=C(OC)C=C2NCCCCCCN(CC)CC)C2=NC=C1.CC3=CC=C(S(=O)(O)=O)C=C3
InChI	1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)
InChI key	LOBPWLFCZDGYKW-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3