SR-58611A

产品名称：

121524-09-2
SR-58611A
Amibegron
[[(7S)-7-[[(2R)-2-(3-Chlorophenyl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydro-2-naphthalenyl]oxy acetic acid ethyl ester hydrochloride

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

SR58611A is a potent, specific b3 adrenergic receptor agonist. The EC₅₀ for reduction of β3-mediated spontaneous motility in rat distal colon sections is 3.5 nM. Minimal anti-depressant efficacious doses for SR58611A are 0.1-0.3 mpk in rodent models.

特点和优势

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基本信息

经验(实验)分子式	C₂₂H₂₆ClNO₄ · HCl
分子量	440.36
MDL编号	MFCD00886563
PubChem化学物质编号	329825649

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -75 to -95°, c = 0.5 in methanol
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	−20℃
SMILES string	ClC1=CC([C@@H](O)CN[C@@H]2CC(C=C(OCC(OCC)=O)C=C3)=C3CC2)=CC=C1.Cl
InChI	1S/C22H26ClNO4.ClH/c1-2-27-22(26)14-28-20-9-7-15-6-8-19(11-17(15)12-20)24-13-21(25)16-4-3-5-18(23)10-16;/h3-5,7,9-10,12,19,21,24-25H,2,6,8,11,13-14H2,1H3;1H/t19-,21-;/m0./s1
InChI key	NQIZCDQCNYCVAS-RQBPZYBGSA-N
Gene Information	human ... ADRB3(155)

安全信息

象形图
警示用语：	Warning
危险声明	H410
预防措施声明	P273 - P501
危险分类	Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable