TVP1022

产品名称：

185517-74-2
TVP1022
(S)-Rasagiline
S-(-)-N-Propargyl-1-aminoindan
(1S)-2,3-Dihydro-N-2-propyn-1-yl-1H-inden-1-amine

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

TVP1022, the S-isomer of rasagiline, an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. TVP1022, a neuroprotective and cytoprotective molecule, is also cardioprotective in rat models. Its activity is believed to involve stabilization of mitochondrial membrane potential, induction of Bcl-2 and activation of the PKC signalling pathway, enhancing the phosphorylation of protein kinase C and glycogen synthase kinase-3β.

基本信息

经验(实验)分子式	C₁₂H₁₃N
分子量	171.24
MDL编号	MFCD09029306
PubChem化学物质编号	329825241
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
溶解性	DMSO: ≥15 mg/mL
储存温度	2-8℃
SMILES string	C#CCN[C@H]1CCc2ccccc12
InChI	1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m0/s1
InChI key	RUOKEQAAGRXIBM-LBPRGKRZSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H400
预防措施声明	P273 - P301 + P312 + P330
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable