产品说明
应用
CDPPB may be used in mGluR5-mediated cell signaling studies.
包装
5, 25 mg in glass bottle
生化/生理作用
CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.
Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C23H16N4O |
分子量 | 364.40 |
PubChem化学物质编号 | 329825248 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: ≥5 mg/mL at warmed to 60 ℃ |
储存温度 | 2-8℃ |
SMILES string | O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N |
InChI | 1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2 |
InChI key | GZHZEGYXLNXEBV-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich