n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate

产品名称：

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate
compound 10i
Cytosporone A n-amyl ester

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate is a Nur77 agonist. Nur77 is a steroid orphan receptor that plays a critical role in regulating proliferation, differentiation and apoptosis. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate, a cytosporone B analog, is a stronger activator of Nur77 than it parent compound. n-Amyl 2-[3,5-dihydroxy-2-(1-nonanoyl)phenyl]acetate treatment causes Nur77 migration to mitochondria, which results in mitochondrial Cyt c release into the cytoplasm and mitochondrial AIF redistribution in both the cytoplasm and nucleus.

特点和优势

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₂₂H₃₄O₅
分子量	378.50
MDL编号	MFCD18632550
PubChem化学物质编号	329770645

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white
溶解性	DMSO: >65 mg/mL
储存温度	2-8℃
SMILES string	CCCCCCCCC(=O)c1c(O)cc(O)cc1CC(=O)OCCCCC
InChI	1S/C22H34O5/c1-3-5-7-8-9-10-12-19(24)22-17(14-18(23)16-20(22)25)15-21(26)27-13-11-6-4-2/h14,16,23,25H,3-13,15H2,1-2H3
InChI key	FCKDHZVFIMRCNM-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable