产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
NS5806 increases peak current amplitude of the potassium channel Kv4.3 (EC50 = 5.3 uM). NS5806 also slows Kv4.3 and Kv4.2 current dacay in channel complexes containing KChIP2. In ventricular cardiomycytes, NS5806 increases transient outward current and reproduces the electrocardiographic profile of Brugada syndrome.
基本信息
| 经验(实验)分子式 | C16H8Br2F6N6O |
| 分子量 | 574.07 |
| MDL编号 | MFCD18432708 |
| PubChem化学物质编号 | 329818416 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to faint yellow |
| 溶解性 | DMSO: >30 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | FC(F)(F)c1cc(NC(=O)Nc2c(Br)cc(Br)cc2-c3nnn[nH]3)cc(c1)C(F)(F)F |
| InChI | 1S/C16H8Br2F6N6O/c17-8-4-10(13-27-29-30-28-13)12(11(18)5-8)26-14(31)25-9-2-6(15(19,20)21)1-7(3-9)16(22,23)24/h1-5H,(H2,25,26,31)(H,27,28,29,30) |
| InChI key | UZWJWROOLOOCPQ-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H413 |
| 预防措施声明 | P273 - P301 + P310 + P330 |
| 危险分类 | Acute Tox. 3 Oral - Aquatic Chronic 4 |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
