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Triparanol

曲帕拉醇

品牌
Sigma-Aldrich
CAS
78-41-1
货号
T5200
规格纯度
≥97% (HPLC), powder
参考价格
2410.17 *本价格含增值税费
促销
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数量
-+
产品名称:
78-41-1
Triparanol
1-(4-(2-Diethylaminoethoxy)phenyl)-1-p-tolyl-2-(4-chlorophenyl)ethanol
曲帕拉醇
产品介绍:

产品说明

应用

Triparanol has been used to inhibit cholesterol biosynthesis in lipid rafts1. Triparanol has also been used as a 3β-hydroxysterol-Δ24-reductase inhibitor to study its effect on delayed-rectifier potassium current (Iks) channels2.

包装

5, 25 mg in glass bottle

生化/生理作用

Triparanol is known to repress Hedgehog signaling in cancer cells and can also inhibit tumor growth3.
Desmosterol Delta24 (D24) reductase inhibitor.

制备说明

Triparanol is soluble in DMSO at 20 mg/ml and is also soluble in alcohol. It is slightly soluble in olive oil and is insoluble in water.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T5200.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式C27H32NO2Cl
分子量438.00
EC 号201-115-0
MDL编号MFCD00865748
PubChem化学物质编号24724632
NACRESNA.77

产品性质

质量水平100
测定≥97% (HPLC)
形式powder
颜色 white to off-white
mp102.9-103.7 ℃
溶解性DMSO: 20 mg/mL
H2O: insoluble
alcohol: soluble
olive oil: slightly soluble
储存温度2-8℃
SMILES stringCCN(CC)CCOc1ccc(cc1)C(O)(Cc2ccc(Cl)cc2)c3ccc(C)cc3
InChI1S/C27H32ClNO2/c1-4-29(5-2)18-19-31-26-16-12-24(13-17-26)27(30,23-10-6-21(3)7-11-23)20-22-8-14-25(28)15-9-22/h6-17,30H,4-5,18-20H2,1-3H3
InChI keySYHDSBBKRLVLFF-UHFFFAOYSA-N
Gene Informationhuman ... DHCR24(1718), EBP(10682)

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H302 - H318
预防措施声明P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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