N-[1,1′-Biphenyl-2-yl]-7-nitro-2,1,3-Benzoxadiazol-4-amine

产品名称：

413611-93-5
10074-G5
N-[1,1′-Biphenyl-2-yl]-7-nitro-2,1,3-Benzoxadiazol-4-amine
Biphenyl-2-yl-(7-nitrobenzo[1,2,5]oxadiazol-4-yl)amine
N-2-Biphenylyl-7-nitro-2,1,3-benzoxadiazol-4-amine

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

10074-G5 is a c-Myc/Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4 (#F3680), specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM). It was discovered that 10074-G5 binds to a different specific binding site (region) of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions.

基本信息

经验(实验)分子式	C₁₈H₁₂N₄O₃
分子量	332.31
MDL编号	MFCD00576774
PubChem化学物质编号	329799918
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	red
溶解性	DMSO: >10 mg/mL
储存温度	room temp
SMILES string	[O-][N+](=O)c1ccc(Nc2ccccc2-c3ccccc3)c4nonc14
InChI	1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H
InChI key	KMJPYSQOCBYMCF-UHFFFAOYSA-N

安全信息

储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3