Terazosin hydrochloride

产品名称：

63074-08-8
Terazosin hydrochloride
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride

产品介绍：

产品说明

一般描述

Terazosin hydrochloride is used to treat hypertension and benign prostatic hyperplasia (BPH). It is metabolised in the liver. It might be associated with dizziness, headache and asthenia. Terazosin hydrochloride is linked to acute generalized exanthematous pustulosis.

应用

Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies⁵. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods⁶.

包装

250 mg in glass bottle
50 mg in poly bottle

生化/生理作用

α₁-adrenoceptor antagonist.

特点和优势

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

制备说明

Terazosin hydrochloride is soluble in water at 19.60 - 20.40 mg/ml and yields a clear, colorless to faint yellow solution. It is also soluble in ethanol at 4 mg/ml. Furthermore, the product is soluble in methanol at 20 mg/ml, with heat as needed, and yields a clear, colorless solution.

基本信息

经验(实验)分子式	C₁₉H₂₅N₅O₄ · HCl
分子量	423.89
MDL编号	MFCD00467965
PubChem化学物质编号	24278740
NACRES	NA.77

产品性质

质量水平	200
测定	≥98% (TLC)
形式	powder
颜色	white to off-white
溶解性	H₂O: soluble 19.60-20.40 mg/mL, clear, colorless to faintly yellow methanol: 20 mg/mL, clear, colorless ethanol: 4 mg/mL
创始人	Abbott
SMILES string	Cl[H].COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)C4CCCO4
InChI	1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H
InChI key	IWSWDOUXSCRCKW-UHFFFAOYSA-N
Gene Information	human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves