产品说明
应用
Cafestol acetate has been used to determine the effects of coffee on heat shock response (HSR).
包装
100 mg in poly bottle
生化/生理作用
Cafestol is a coffee-specific diterpene. It has anti-carcinogenic and anti-inflammatory activities. Cafestol stimulates apoptosis in cells associated with colorectal and renal cancer (Caki cells). It is used to study mechanisms of anti-oxidation related to hydrogen peroxide induced oxidative stress and DNA damage. Cafestol increases the level of glutathione (GSH), by stimulating γ-glutamylcysteine synthetase. It acts as a chemopreventive agent by inducing cytochrome P-450.
其他说明
Furan-containing diterpene from green coffee beans.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C1305.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
基本信息
经验(实验)分子式 | C22H30O4 |
分子量 | 358.47 |
MDL编号 | MFCD00133152 |
PubChem化学物质编号 | 24892399 |
NACRES | NA.79 |
产品性质
质量水平 | 100 |
测定 | ≥98% |
形式 | powder |
technique(s) | HPLC: suitable |
颜色 | white to off-white |
储存温度 | 2-8℃ |
SMILES string | CC(=O)OCC1(O)CC23CCC4c5ccoc5CCC4(C)C2CCC1C3 |
InChI | 1S/C22H30O4/c1-14(23)26-13-22(24)12-21-9-5-17-16-7-10-25-18(16)6-8-20(17,2)19(21)4-3-15(22)11-21/h7,10,15,17,19,24H,3-6,8-9,11-13H2,1-2H3 |
InChI key | PTGGVIKFNQSFBY-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich