产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS.
基本信息
| 经验(实验)分子式 | C17H18N4O·HCl |
| 分子量 | 330.81 |
| MDL编号 | MFCD09028027 |
| PubChem化学物质编号 | 329825350 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | H2O: ≥5 mg/mL at warmed |
| 储存温度 | 2-8℃ |
| SMILES string | CN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl |
| InChI | 1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H |
| InChI key | FNYQZOVOVDSGJH-UHFFFAOYSA-N |
| Gene Information | human ... HTR3A(3359) |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H319 - H412 |
| 预防措施声明 | P273 - P301 + P310 + P330 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Irrit. 2 |
| 储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
