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Fluspirilene

品牌
Sigma-Aldrich
CAS
1841-19-6
货号
F100
包装型号
规格纯度
参考价格
2102.31 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
1841-19-6
Fluspirilene
8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one
R 6218
产品介绍:

产品说明

应用

Fluspirilene has been used as a neuroleptic drug to study its effects on human ether-a-go-go related gene (HERG).
Fluspirilene has been used to study its cytotoxicity effect on malignant glioma.

包装

10, 50 mg in glass bottle

生化/生理作用

Fluspirilene has a potential to inhibit the activity of cyclin-dependent kinase 2 (CDK2). It is an effective anti-cancer agent used for treating human hepatocellular carcinoma.
Fluspirilene is a dopamine receptor antagonist. It also acts as a calcium channel blocker. Fluspirilene is an antipsychotic agent and exhibits neuoleptic properties. It exhibits therapeutic effects against glioblastoma and Schizophrenia.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式C29H31F2N3O
分子量475.57
EC 号217-418-6
MDL编号MFCD00055137
PubChem化学物质编号24277915
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式solid
颜色 white
溶解性DMSO: ≥20 mg/mL
H2O: insoluble
ethanol: soluble
创始人Johnson & Johnson
储存温度room temp
SMILES stringFc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5
InChI1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35)
InChI keyQOYHHIBFXOOADH-UHFFFAOYSA-N
Gene Informationhuman ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

Sigma-Aldrich

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