产品说明
特异性
The conjugates will identify and quantitate cells containing intracellular forms of human IL-4.
免疫原
recombinant human IL-4
包装
100 test in glass bottle
生化/生理作用
Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The signaling stimulated by IL-4 by binding to its receptors leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. IL-4 mediates endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. The coupling of Carboxyfluorescein to Anti-Interleukin-4 antibody allows for flow cytometry applications.
外形
Solution in saline containing up to 0.5% bovine serum albumin and up to 0.1% of sodium azide as a preservative.
制备说明
Purified antibody is conjugated to carboxyfluorescein (FITC).
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | carboxyfluorescein conjugate |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 3007.11, monoclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| 储存条件 | protect from light |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P05112 |
| 运输 | wet ice |
| 储存温度 | 2-8℃ |
| Gene Information | human ... IL4(3565) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
