产品说明
一般描述
Mismatch repair protein 2 (MSH2) possesses four domains and belongs to the mismatch repair (MMR) gene family. The gene encoding this protein is localized on human chromosome 2p21.
免疫原
recombinant human mismatch repair protein 2 (MSH2).
生化/生理作用
Mismatch repair protein 2 (MSH2) plays a very important role in the DNA mismatch repair system. It repairs DNA damage which is induced by drugs. MSH2 dysfunction has been associated with nonpolyposis colorectal cancer (Lynch syndrome).
外形
Contains 15 mM sodium azide.
基本信息
| MDL编号 | MFCD00282379 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | tissue culture supernatant |
| antibody product type | primary antibodies |
| 克隆 | 2MSH01, monoclonal |
| 分子量 | antigen 102 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25 |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P43246 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MSH2(4436) |
Sigma-Aldrich
m.cnreagent.com
