产品说明
一般描述
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is an inositol phospholipid, which accounts for approximately 0.05-0.1% of total cellular phosphatidylinositol (PI). In fungi and higher eukaryotes, this less abundant phosphoinositide is present in the endosomal and lysosomal membranes.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
生化/生理作用
Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) is capable of activating ion channels on endosomes and lysosomes. It also activates mammalian target of rapamycin complex 1 (mTORC1) in yeast and in some mammalian cell types.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (850174P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850174P-100ug)
基本信息
经验(实验)分子式 | C21H50N3O19P3 |
分子量 | 741.55 |
NACRES | NA.25 |
产品性质
测定 | >99% (TLC) |
形式 | powder |
包装 | pkg of 1 × 100 μg (with stopper and crimp cap (850174P-100ug)) pkg of 1 × 500 μg (with stopper and crimp cap (850174P-500ug)) |
manufacturer/tradename | Avanti Polar Lipids 850174P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](OP(O)([O-])=O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCC)=O)COC(CCCCC)=O.[NH4+].[NH4+].[NH4+] |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich