产品说明
一般描述
Ceramide is one of the products of sphingolipid metabolism. The ceramides differ in their acyl chain length.
应用
C8 PEG750 Ceramide has been used in ceramide liposome formulation to test a method for pH-dependent fusion between liposomes and cellular membranes using a pH low insertion peptide. It is also suitable for use in nanoliposomal formulation.
生化/生理作用
Poly-ethylene glycol (PEG) conjugated to ceramides are applicable as liposomal carriers, enclosing drug molecules. They are known to increase the circulation longevity of the drug due to its neutral surface electrostatic charge. This is inferred to decrease the negative surface charge of the liposomes preventing the release of positively charged encapsulated drug molecule.
包装
5 mL Amber Glass Screw Cap Vial (880670P-25mg)
产品性质
形式 | powder |
包装 | pkg of 1 × 25 mg (880670P-25mg) |
manufacturer/tradename | Avanti Polar Lipids 880670P |
运输 | dry ice |
储存温度 | −20℃ |
SMILES string | O=C(CCC(OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC)=O)OOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC.C=C |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich