产品说明
一般描述
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
免疫原
gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.
应用
gp120 antibody can be used for Western blot at 1 - 2 μg/mL.
外形
Supplied in PBS containing 0.02% sodium azide.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | human immunodeficiency virus 1 |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: suitable |
| 同位素/亚型 | IgG |
| UniProt登记号 | P04578 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human immunodeficiency virus 1 ... gp120(155971) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
