产品说明
一般描述
Myosin light chain kinase (MLCK) is a serine/threonine kinase and the gene encoding it is localized on human chromosome 3q21.1.
生化/生理作用
Myosin light chain kinase (MLCK) is activated by the binding of Ca2+/calmodulin. It has a role in smooth muscle contraction. The kinase phosphorylates the regulatory light chain of smooth muscle myosin. This stimulates ATPase activity of the myosin heads and leads to the myosin power stroke, which is crucial for muscle contraction. MLCK also assists the interaction of myosin with actin. Loss of function of the protein has been linked to megacystis microcolon intestinal hypoperistalsis syndrome.
外形
Supplied in PBS with 0.09% (W/V) sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 210715 Da |
| species reactivity | human, mouse |
| technique(s) | immunohistochemistry: 1:50-1:100 western blot: 1:1000 |
| NCBI登记号 | NP_444253.3 |
| UniProt登记号 | Q15746 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MYLK(4638) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
