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Anti-phospho-ITGB3 (pTyr785) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300224
规格纯度
affinity isolated antibody
参考价格
4618.16 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-phospho-ITGB3 (pTyr785) antibody produced in rabbit
Anti-GP3A antibody produced in rabbit
Anti-GPIIIa antibody produced in rabbit
Anti-CD61 antibody produced in rabbit
Anti-integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) antibody produced in rabbit
产品介绍:

产品说明

免疫原

Peptide sequence around phosphorylation site of tyrosine 785 (I-T-Y(p)-R-G), according to the protein ITGB3.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00211790
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~110 kDa
species reactivityrat, human, mouse
浓度1 mg/mL
technique(s)western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(I-T-YP-R-G)
NCBI登记号NP_000203.2
UniProt登记号P05106
运输wet ice
储存温度−20℃
Gene Informationhuman ... ITGB3(3690)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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