产品说明
免疫原
Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L), according to the protein KRT8.
特点和优势
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目标描述
Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~55 kDa |
| species reactivity | human |
| 浓度 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (L-L-SP-P-L) |
| NCBI登记号 | NP_002264.1 |
| UniProt登记号 | P05787 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KRT8(3856) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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