您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > c-KIT (N822K), active, GST tagged human

c-KIT (N822K), active, GST tagged human

品牌
Sigma-Aldrich
CAS
1537224-27-3
货号
SRP5300
规格纯度
PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6468.88 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
1537224-27-3
c-KIT (N822K), active, GST tagged human
PBT
SCFR
CD117
产品介绍:

产品说明

一般描述

c-KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. c-KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in c-KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

制备说明

After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO®
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity1.5-2.3 nmol/min·mg
分子量 ~73 kDa
NCBI登记号NM_000222
application(s)cell analysis
运输dry ice
储存温度−70℃
Gene Informationhuman ... KIT(3815)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品